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Vitamin K2, also known as menaquinone, in which MK-7 is derived from synthesis and fermentation. The types of K2 include tetraene naphthoquinone (MK-4), hexaene naphthoquinone (MK-6), and heptaene naphthoquinone (MK-7). Research shows that MK-7 degradation can form MK-4.
Compared with other forms, the biological activity of MK-7 is superior to MK-4 and K1. MK-7 has higher bioavailability and longer half-life than MK-4. And MK-7 has good absorption efficiency and is currently the main dosage form.
My factory supplies vitamin raw materials, including powders, oils, and customized vitamin supplements.
1. It has the function of preventing and treating osteoporosis. MK-7 can increase bone density, improve bone quality, strength, and collagen production. MK-7 can stimulate osteoblast differentiation, upregulate bone marker gene expression, and promote bone formation.
MK-7 is associated with reducing cardiovascular and coronary artery calcification.
Description
Product CAS No.
Shelf Life Quantity Lot No.
Production Date
CERTIFICATE OF ANALYSIS
Vitamin K2(Menatetrenone MK-4) 98% 863-61-6
24 Months 59kg 20190601
2019/08/29
Expiration Date 2021/08/28
Storage Store in a dry & cool place, keep away from light, moisture, heat & oxygen
Chemical & Physical Analysis
Appearance Yellow powder
Yellow powder
Internal
MK-4 (HPLC) % ≥98
regarding to the principal spot from the sample
98.3 JP15
Cis-isomer
Solubility
solution is not more intense than the spot from the standard solution
Easily soluble in n-hexane, soluble in ethanol, slightly soluble in methanol, almost insoluble in water
Complies JP15
Complies Internal
| Condition
Clarity in Hexane Absorption in isooctane |
No offensive taste and smell Clear and Yellow
325nm-327nm |
Complies Complies
Complies |
Internal Internal
Internal |
| Absorbance Ratio A1/A2 | 0.32-0.38 | 0.36 | |
| Melting Point(℃) | ≥35.0 ℃ | 37.0 ℃ | JP15<2.60> |
| Arsenic ppm | ≤2 | ＜0.1 | GB 5009.11 |
| Lead ppm | ≤2 | ＜0.1 | GB 5009.12 |
| Mercury ppm | ≤0.2 | ＜0.1 | GB 5009.17 |
| Cadmium ppm | ≤0.3 | ＜0.3 | GB 5009.15 |
| Water % | ≤0.5 | ＜0.5 | JP15<2.48> |
| Residue on Ignition % | ≤0.1 | ＜0.1 | JP15<2.44> |
Menaquinone Not appear royal purple Not appear royal purple
JP15
Microbiological Analysis
| Characterisitic | Unit | Specifications | Results | Method of Analys |
| Colonies Number | CFU/g | ≤1000 | ＜10 | GB 4789.2 |
| Salmonella SP. | 0/25g | Not detected | GB 4789.4 | |
| Staphylococcus | 0/25g | Not detected | GB 4789.10 | |
| E. Coli | MPN/g | 0/25g | Not detected | GB 4789.3 |
| Residual Solvent | ||||
| Characterisitic | Unit | Specifications | Results | Method of Analys |
| Ethanol | % | ≤0.5 | ＜0.01 | GC |
| Acetone | % | ≤0.5 | ＜0.13 | GC |
| Test: | Jiakai Liao | Check: Ze Lei |
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